An In Vitro Test for Drug Resistance in Haemonchus contortus
نویسنده
چکیده
A cambendazole-resistant (CR) strain of Haemonchus contortus, the large stomach nematode of sheep, had similar in vitro growth characteristics compared to the parent strain (BPL). When the in vitro cultivation system was modified to detect drug resistance: (1) exsheathed infective larvae of the BPL strain did not develop in a culture medium with a concentration of 2.5 /ug/rnl thiabendazole (TBZ), but the CR strain developed to the mid-4th larval stage in 6 days at the same concentration of TBZ; and, (2) larvae of both strains of//, contortus were killed prior to or in the 3rd molt in a culture medium with 2.5 /ug/ml levamisole.
منابع مشابه
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